Tinfunqué is a huge floodplain in the humid Chaco, a mosaic of marshes, palm groves and grasslands in the Pilcomayo River basin. Route PY12 runs right through it, and in the dry season you can spot storks, herons and ducks from the road and, with luck, guasu puku (marsh deer), aguara guasu (maned wolf) or mborevi (tapir). There's no tourist infrastructure: almost the entire area is made up of private estancias that coexist with conservation. It's a destination for self-sufficient travelers and bird lovers, ideally with a local guide or a prior contact at one of the estancias.

Its name is thought to come from the Nivaclé word Tinjoqee, “natural watering hole.” In 1924 Bolivia founded a fort here, and the area remained in Paraguay after the 1938 peace treaty. It was created as a national park on May 4, 1966 (Decree 18,205), covering some 241,000 hectares; it was declared a Ramsar site in 1995 and, on November 30, 2016, reclassified as a Managed Resource Reserve.